Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26318227 | 0.86 | MAPT (0.35) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19836357 | 0.85 | MAPT (0.36) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19752970 | 0.83 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3ESR1ESR2 | |
| SCHEMBL10028646 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ESR1ESR2 | |
| SCHEMBL18533959 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ESR1ESR2 | |
| SCHEMBL13539978 | 0.79 | SLC6A2 (0.47) | SLC6A2SLC6A4SLC6A3ESR1ESR2 | |
| SCHEMBL23612568 | 0.78 | APP (0.46) | MEN1ALDH1A1POLBKMT2A | |
| SCHEMBL19346868 | 0.78 | ALDH1A1 (0.37) | MEN1ALDH1A1KMT2A | |
| SCHEMBL10031189 | 0.78 | SLC6A2 (0.49) | SLC6A2SLC6A4SLC6A3ESR1ESR2 | |
| SCHEMBL8640292 | 0.78 | ESR1 (0.46) | SLC6A2SLC6A4SLC6A3ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970197-B1 | COPPER COMPLEXES WITH POLYPODAL LIGANDS CONNECTED THROUGH A COMMON NITROGEN OR PHOSPHOR ATOM AS WELL AS THEIR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2018-04-11 | — | — | EP | disclosed |