SCHEMBL20040141

SCHEMBL20040141

CCC/C(=N\C)c1cccc(OC)c1

nearest known ligand 0.51

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.51
RAB9A P51151 3/20 0.51
CES2 O00748 1/20 0.50
CES1 P23141 1/20 0.50
MTNR1B P49286 3/20 0.49
PARP1 P09874 1/20 0.47
PRSS1 P07477 1/20 0.47
PRSS2 P07478 1/20 0.47
PRSS3 P35030 1/20 0.47
TAS1R3 Q7RTX0 1/20 0.47
TAS1R1 Q7RTX1 1/20 0.47
ALDH1A1 P00352 3/20 0.44
GAA P10253 2/20 0.44
MAPT P10636 2/20 0.43
MTNR1A P48039 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
TP53 P04637 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22736822 0.83 NPC1 (0.54) NPC1RAB9ACES2CES1PARP1
SCHEMBL19380927 0.78 MEN1 (0.52) NPC1RAB9ACES2CES1PARP1
SCHEMBL15164585 0.77 GAA (0.58) NPC1RAB9ACES2CES1PARP1
SCHEMBL4637827 0.77 CES2 (0.62) NPC1RAB9ACES2CES1MTNR1B
SCHEMBL4701315 0.75 NPC1 (0.53) NPC1RAB9ACES2CES1MTNR1B
SCHEMBL4701313 0.75 NPC1 (0.53) NPC1RAB9ACES2CES1MTNR1B
SCHEMBL9687402 0.74 CES2 (0.50) NPC1RAB9ACES2CES1MTNR1B
SCHEMBL6053475 0.74 CES2 (0.50) NPC1RAB9ACES2CES1MTNR1B
SCHEMBL12083041 0.74 NPC1 (0.76) NPC1RAB9ACES2CES1PARP1
SCHEMBL25455101 0.73 NPC1 (0.54) NPC1RAB9ACES2CES1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3305782-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DIODE COMPRISING SAME SFC Co., Ltd. (KR) 2018-04-11 EP disclosed