Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15006373 | 0.93 | KMT2A (0.40) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL20040348 | 0.89 | KMT2A (0.34) | KMT2AKDM4EMAPTHTT | |
| SCHEMBL15259411 | 0.86 | ALB (0.42) | KMT2AKDM4EMAPTHTTNPC1 | |
| SCHEMBL20040343 | 0.85 | KMT2A (0.39) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL11925960 | 0.84 | GAA (0.39) | GAAALDH1A1 | |
| SCHEMBL20040326 | 0.82 | MEN1 (0.36) | KMT2AMAPTMEN1 | |
| SCHEMBL20040443 | 0.81 | NPC1 (0.51) | KMT2AKDM4EMAPTHTTNPC1 | |
| SCHEMBL19771690 | 0.80 | KMT2A (0.44) | KMT2AKDM4EMAPTHTTGAA | |
| SCHEMBL15006372 | 0.80 | NPC1 (0.50) | KMT2AKDM4EMAPTHTTNPC1 | |
| SCHEMBL22130749 | 0.80 | NPC1 (0.40) | KMT2AKDM4EMAPTHTTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673259-B1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2018-04-11 | — | — | EP | disclosed |