Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15006372 | 0.99 | NPC1 (0.50) | NPC1RAB9ALMNAKDM4EKMT2A | |
| SCHEMBL15259411 | 0.87 | ALB (0.42) | NPC1RAB9ALMNAKDM4EKMT2A | |
| SCHEMBL22130749 | 0.87 | NPC1 (0.40) | NPC1RAB9ALMNAKDM4EKMT2A | |
| SCHEMBL15006373 | 0.84 | KMT2A (0.40) | NPC1RAB9ALMNAKDM4EKMT2A | |
| SCHEMBL19771690 | 0.83 | KMT2A (0.44) | NPC1RAB9ALMNAKDM4EKMT2A | |
| SCHEMBL20040345 | 0.81 | KMT2A (0.38) | NPC1RAB9ALMNAKDM4EKMT2A | |
| SCHEMBL2350932 | 0.78 | ALDH1A1 (0.44) | NPC1RAB9AMAPTHPGD | |
| SCHEMBL11926962 | 0.78 | LMNA (0.37) | NPC1RAB9ALMNAKDM4EKMT2A | |
| SCHEMBL9751347 | 0.77 | TDP1 (0.55) | NPC1RAB9ALMNAMAPTHPGD | |
| SCHEMBL13611354 | 0.77 | PRSS1 (0.47) | NPC1RAB9ALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2673259-B1 | AMINO ACID DERIVATIVES AND ABSORBABLE POLYMERS THEREFROM | BEZWADA BIOMEDICAL LLC (US) | 2018-04-11 | — | — | EP | disclosed |