Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | GPR3 | P46089 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17228181 | 0.86 | KDM4E (0.51) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL20040376 | 0.86 | LMNA (0.45) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL17245314 | 0.83 | KDM4E (0.47) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL17990223 | 0.83 | KDM4E (0.47) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL17227999 | 0.83 | KDM4E (0.47) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL9890222 | 0.82 | KDM4E (0.46) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL17990246 | 0.82 | KDM4E (0.46) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL12270939 | 0.81 | KDM4E (0.47) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL17245927 | 0.81 | MAPT (0.42) | SMN1; SMN2ATMLMNAHIF1AKDM4E | |
| SCHEMBL17246293 | 0.81 | LMNA (0.39) | SMN1; SMN2ATMLMNAHIF1AGPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053918-B1 | 2-carbazole substituted benzimidazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |