Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 12/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.32 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5231980 | 0.77 | ADRB2 (0.41) | ALDH1A1TSHRPTGS2FFAR4MEN1 | |
| SCHEMBL2006705 | 0.77 | ADRB2 (0.41) | ALDH1A1TSHRPTGS2FFAR4MEN1 | |
| SCHEMBL30239224 | 0.74 | ACACB (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL4934500 | 0.74 | ACACB (0.45) | ALDH1A1MEN1KMT2A | |
| SCHEMBL17061935 | 0.69 | GRN (0.31) | — | |
| SCHEMBL16770615 | 0.69 | GRN (0.31) | — | |
| SCHEMBL28336016 | 0.69 | GRN (0.31) | — | |
| SCHEMBL17061937 | 0.69 | GRN (0.31) | — | |
| SCHEMBL27413791 | 0.69 | GRN (0.31) | — | |
| SCHEMBL17601590 | 0.69 | KMT2A (0.36) | ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7960365-B2 | Compounds with medicinal effects due to interaction with the glucocorticoid receptor | N.V. ORGANON (NL) | 2011-06-14 | — | — | US | disclosed |