Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.34 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457585 | 0.83 | HDAC3 (0.47) | MAPTTMPRSS4P2RX1HDAC3HDAC1 | |
| SCHEMBL15693713 | 0.78 | FFAR4 (0.42) | MAPTALDH1A1MEN1GAAALOX12 | |
| SCHEMBL131766 | 0.78 | MAPT (0.46) | MAPTALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL20040903 | 0.74 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL16729395 | 0.72 | KMT2A (0.50) | MAPTALDH1A1MEN1GAAALOX12 | |
| SCHEMBL11955180 | 0.72 | FFAR4 (0.39) | MAPTALDH1A1MEN1GAAALOX12 | |
| SCHEMBL18860247 | 0.72 | HDAC3 (0.42) | MAPTALDH1A1RXFP1TMPRSS4P2RX1 | |
| SCHEMBL2092157 | 0.71 | PLAU (0.50) | ALDH1A1MEN1GAAALOX12KMT2A | |
| SCHEMBL1336292 | 0.71 | PARP10 (0.51) | MAPTALDH1A1MEN1GAAALOX12 | |
| SCHEMBL16907615 | 0.71 | ALDH1A1 (0.62) | MAPTALDH1A1MEN1GAAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2864289-B1 | CYCLOPROPANECARBOXAMIDO-SUBSTITUTED AROMATIC COMPOUNDS AS ANTI-TUMOR AGENTS | CB THERAPEUTICS INC (KY) | 2018-04-11 | — | — | EP | disclosed |