Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 11/20 | 0.46 |
| ▸ | CLK3 | P49761 | 11/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.46 |
| ▸ | WNT1 | P04628 | 9/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12370161 | 0.87 | CLK2 (0.48) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL12370152 | 0.86 | WNT1 (0.45) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL17557478 | 0.85 | WNT1 (0.55) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL12370142 | 0.85 | CLK2 (0.55) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL12370134 | 0.85 | CLK2 (0.52) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL12396644 | 0.84 | CLK2 (0.41) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL20041589 | 0.84 | CLK2 (0.47) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL12370148 | 0.84 | CLK2 (0.55) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL12370144 | 0.83 | CLK2 (0.57) | CLK2CLK3DYRK1AWNT1TGFBR1 | |
| SCHEMBL12370005 | 0.83 | WNT1 (0.55) | CLK2CLK3DYRK1AWNT1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305073-A1 | 1H-PYRAZOLO[3,4-B]PYRIDINES AND THERAPEUTIC USES THEREOF | Samumed, LLC (US) | 2018-04-11 | — | — | EP | disclosed |