Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | IRAK4 | Q9NWZ3 | 11/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 4/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041419 | 0.90 | NPC1 (0.40) | NPC1RAB9AIRAK4TGFBR1CCR1 | |
| SCHEMBL20041609 | 0.82 | NPC1 (0.45) | NPC1RAB9A | |
| SCHEMBL17507238 | 0.82 | NPC1 (0.45) | NPC1RAB9AIRAK4PDE10A | |
| SCHEMBL17507364 | 0.81 | NPC1 (0.44) | NPC1RAB9A | |
| SCHEMBL20041610 | 0.81 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL17507363 | 0.80 | NPC1 (0.54) | NPC1RAB9A | |
| SCHEMBL17507245 | 0.79 | NPC1 (0.51) | NPC1RAB9A | |
| SCHEMBL18701303 | 0.78 | NPC1 (0.46) | NPC1RAB9A | |
| SCHEMBL18701361 | 0.78 | NPC1 (0.46) | NPC1RAB9A | |
| SCHEMBL18701299 | 0.77 | NPC1 (0.50) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |