Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041421 | 0.97 | TP53 (0.45) | TP53MAPTENPP3RXFP1TDP1 | |
| SCHEMBL20041619 | 0.94 | TP53 (0.43) | TP53MAPTENPP3RXFP1TDP1 | |
| SCHEMBL17507335 | 0.90 | HPGD (0.39) | TP53MAPTFLT3NPC1HPGD | |
| SCHEMBL17507333 | 0.84 | HPGD (0.42) | TP53MAPTNPC1HPGDRAB9A | |
| SCHEMBL17507339 | 0.84 | FLT3 (0.45) | TP53MAPTTDP1FLT3THRB | |
| SCHEMBL20041679 | 0.83 | FLT3 (0.41) | TP53MAPTTDP1FLT3NPC1 | |
| SCHEMBL17507336 | 0.82 | HPGD (0.40) | TP53MAPTFLT3NPC1HPGD | |
| SCHEMBL17507250 | 0.81 | TP53 (0.44) | TP53MAPTENPP3RXFP1THRB | |
| SCHEMBL20041631 | 0.81 | FLT3 (0.40) | TP53MAPTFLT3HPGDSMN1; SMN2 | |
| SCHEMBL20041655 | 0.80 | TP53 (0.45) | TP53MAPTENPP3RXFP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |