SCHEMBL20041633

SCHEMBL20041633

Pc1ccc2nc3oc4ccccc4n3c2c1

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 1/20 0.33
LMNA P02545 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17491659 0.82 NPC1 (0.66) NPC1RAB9AKDM4EALDH1A1LMNA
SCHEMBL17491665 0.82 NPC1 (0.51) NPC1RAB9AKDM4EALDH1A1LMNA
SCHEMBL20560869 0.82 NPC1 (0.51) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL17507245 0.82 NPC1 (0.51) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL17507363 0.81 NPC1 (0.54) NPC1RAB9AKDM4EALDH1A1LMNA
SCHEMBL20041610 0.78 NPC1 (0.51) NPC1RAB9AKDM4EALDH1A1LMNA
SCHEMBL17507425 0.78 NPC1 (0.51) NPC1RAB9AKDM4EALDH1A1LMNA
SCHEMBL18701364 0.78 NPC1 (0.51) NPC1RAB9AKDM4EALDH1A1LMNA
SCHEMBL20041705 0.78 RAB9A (0.48) NPC1RAB9AKDM4EALDH1A1HPGD
SCHEMBL24575878 0.77 RAB9A (0.50) NPC1RAB9AKDM4EALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2982676-B1 Benzimidazo[2,1-B]benzoxazoles for electronic applications IDEMITSU KOSAN CO (JP) 2018-04-11 EP disclosed