Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041551 | 0.94 | MEN1 (0.46) | THRBHPGDKMT2AMEN1KDM4E | |
| SCHEMBL20041689 | 0.92 | MEN1 (0.44) | HPGDPOLBKMT2AMEN1KDM4E | |
| SCHEMBL17507390 | 0.92 | MEN1 (0.44) | HPGDPOLBKMT2AMEN1KDM4E | |
| SCHEMBL20041428 | 0.91 | MAPT (0.50) | THRBHPGDKMT2AMEN1KDM4E | |
| SCHEMBL20041554 | 0.90 | MEN1 (0.43) | THRBHPGDKMT2AMEN1KDM4E | |
| SCHEMBL20041691 | 0.89 | MAPT (0.51) | THRBHPGDKMT2AMEN1KDM4E | |
| SCHEMBL20041528 | 0.89 | MEN1 (0.44) | THRBHPGDKMT2AMEN1KDM4E | |
| SCHEMBL20041525 | 0.89 | MEN1 (0.44) | THRBHPGDKMT2AMEN1KDM4E | |
| SCHEMBL16920049 | 0.88 | KMT2A (0.47) | THRBHPGDKMT2AMEN1TP53 | |
| SCHEMBL20041455 | 0.88 | MAPT (0.50) | THRBHPGDKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |