Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | TP53 | P04637 | 7/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041455 | 0.99 | MAPT (0.50) | MAPTTP53RXFP1THRBHSD17B10 | |
| SCHEMBL20041428 | 0.99 | MAPT (0.50) | MAPTTP53RXFP1THRBHSD17B10 | |
| SCHEMBL20929615 | 0.95 | MAPT (0.51) | MAPTTP53RXFP1THRBHSD17B10 | |
| SCHEMBL20041528 | 0.92 | MEN1 (0.44) | MAPTTP53RXFP1THRBHSD17B10 | |
| SCHEMBL20041525 | 0.92 | MEN1 (0.44) | MAPTTP53RXFP1THRBHSD17B10 | |
| SCHEMBL20041554 | 0.91 | MEN1 (0.43) | MAPTTP53RXFP1THRBHSD17B10 | |
| SCHEMBL20041687 | 0.89 | THRB (0.47) | MAPTTP53THRBHSD17B10MEN1 | |
| SCHEMBL17507390 | 0.89 | MEN1 (0.44) | MAPTTP53RXFP1HSD17B10MEN1 | |
| SCHEMBL20041689 | 0.89 | MEN1 (0.44) | MAPTTP53RXFP1HSD17B10MEN1 | |
| SCHEMBL20041551 | 0.89 | MEN1 (0.46) | MAPTTP53RXFP1THRBHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |