Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15631678 | 0.98 | KDM4E (0.42) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL25569975 | 0.85 | ALDH1A1 (0.55) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20041553 | 0.85 | KDM4E (0.50) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20893154 | 0.84 | MGAM (0.40) | KDM4EGAAATML3MBTL1MGAM | |
| SCHEMBL20041527 | 0.82 | KDM4E (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL15631625 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20041534 | 0.80 | NPC1 (0.35) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL20893112 | 0.80 | NPY5R (0.39) | KDM4EGAAATML3MBTL1PGR | |
| SCHEMBL22357668 | 0.78 | KDM4E (0.46) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA | |
| SCHEMBL16693319 | 0.78 | CHEK2 (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |