Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 7/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TYMS | P04818 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041658 | 0.97 | NPC1 (0.48) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL17507251 | 0.94 | NPC1 (0.50) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL17507250 | 0.92 | TP53 (0.44) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL20041655 | 0.91 | TP53 (0.45) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL17507244 | 0.89 | NPC1 (0.43) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL18701469 | 0.88 | NPC1 (0.43) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL20041610 | 0.86 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL17507240 | 0.85 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL20041419 | 0.83 | NPC1 (0.40) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL17507239 | 0.82 | NPC1 (0.42) | NPC1RAB9AALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-B1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | IDEMITSU KOSAN CO (JP) | 2018-04-11 | — | — | EP | disclosed |