Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17507238 | 0.90 | NPC1 (0.45) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL20041419 | 0.82 | NPC1 (0.40) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL20041722 | 0.82 | NPC1 (0.47) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL17507251 | 0.82 | NPC1 (0.50) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL20041658 | 0.80 | NPC1 (0.48) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL20041655 | 0.77 | TP53 (0.45) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL17507240 | 0.77 | NPC1 (0.51) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL17507250 | 0.76 | TP53 (0.44) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL17491659 | 0.75 | NPC1 (0.66) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 | |
| SCHEMBL17507255 | 0.75 | RAB9A (0.48) | NPC1RAB9AHSD17B10TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2982676-A1 | Benzimidazo[2,1-B]benzoxazoles for electronic applications | Idemitsu Kosan Co., Ltd. (JP) | 2016-02-10 | — | — | EP | disclosed |