SCHEMBL20041756

SCHEMBL20041756

N/N=C\N(N)CNc1nonc1C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
STAT5B P51692 3/20 0.41
FURIN P09958 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20048208 0.83 STAT5B (0.39) STAT5B
SCHEMBL20041810 0.82 STAT5B (0.42) STAT5B
SCHEMBL20048222 0.74 STAT5B (0.46) STAT5BFURIN
SCHEMBL22096033 0.68 STAT5B (0.40) STAT5B
SCHEMBL23615873 0.67 STAT5B (0.47) STAT5BFURIN
SCHEMBL14399057 0.66 STAT5B (0.52) STAT5B
SCHEMBL20048213 0.64 STAT5B (0.44) STAT5BFURIN
SCHEMBL20048219 0.64 STAT5B (0.44) STAT5BFURIN
SCHEMBL20041805 0.60 STAT5B (0.45) STAT5BFURIN
SCHEMBL3482891 0.60 STAT5B (0.38) STAT5B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3305783-A1 NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER Freie Universität Berlin (DE) 2018-04-11 EP disclosed