Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT5B | P51692 | 3/20 | 0.45 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 11/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20041804 | 0.81 | STAT5B (0.42) | STAT5BFURINHDAC1HDAC3HDAC2 | |
| SCHEMBL23615898 | 0.77 | CYP1A2 (0.45) | FURINHDAC1HDAC3HDAC2MAPK1 | |
| SCHEMBL23615873 | 0.69 | STAT5B (0.47) | STAT5BFURIN | |
| SCHEMBL20048222 | 0.68 | STAT5B (0.46) | STAT5BFURIN | |
| SCHEMBL14397810 | 0.68 | TDP1 (0.46) | STAT5BHDAC1HDAC3HDAC2HDAC4 | |
| Hydrochloric Acid SCHEMBL29008104 | 0.66 | HDAC1 (0.52) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL1697077 | 0.66 | HDAC1 (0.52) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL22096008 | 0.65 | ALDH1A1 (0.67) | STAT5BALDH1A1KDM4EKMT2A | |
| SCHEMBL26921523 | 0.65 | HDAC1 (0.51) | HDAC1HDAC3HDAC2HDAC4HDAC7 | |
| SCHEMBL22096016 | 0.64 | STAT5B (0.81) | STAT5BHDAC6ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305783-A1 | NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER | Freie Universität Berlin (DE) | 2018-04-11 | — | — | EP | disclosed |