Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1898219 | 0.88 | ORAI1 (0.76) | ORAI1CRACR2A | |
| SCHEMBL12661308 | 0.76 | ORAI1 (0.74) | ORAI1CRACR2A | |
| SCHEMBL20006292 | 0.76 | CRACR2A (0.60) | ORAI1CRACR2A | |
| SCHEMBL1666597 | 0.76 | ORAI1 (0.77) | ORAI1CRACR2A | |
| SCHEMBL30096552 | 0.76 | ORAI1 (0.77) | ORAI1CRACR2A | |
| Hydrochloric Acid SCHEMBL1897438 | 0.75 | ORAI1 (0.76) | ORAI1CRACR2A | |
| SCHEMBL1896617 | 0.75 | CRACR2A (0.64) | ORAI1CRACR2A | |
| SCHEMBL30096564 | 0.75 | CRACR2A (0.64) | ORAI1CRACR2A | |
| SCHEMBL1668139 | 0.74 | ORAI1 (1.00) | ORAI1CRACR2A | |
| SCHEMBL1666724 | 0.73 | ORAI1 (0.75) | ORAI1CRACR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509974-B1 | PYRAZOLES DERIVATIVES MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL AND METHODS FOR TREATMENT OF NON-SMALL CELL LUNG CANCER | RHIZEN PHARMACEUTICALS S A (CH) | 2018-04-11 | — | — | EP | disclosed |