SCHEMBL20041787

SCHEMBL20041787

CC(=O)OC(C)OC(=O)/C(CNCn1cnnn1)=N/ON

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
STAT5B P51692 2/20 0.34
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22096009 0.65 STAT5B (0.73) STAT5BTP53MAPT
SCHEMBL22281721 0.57 TP53 (0.43) STAT5BTP53MAPT
SCHEMBL20942702 0.55 TP53 (0.55) TP53MAPT
SCHEMBL48809 0.55
SCHEMBL987906 0.55 TSHR (0.65) MAPT
SCHEMBL315947 0.54 ALDH1A1 (0.52) STAT5BTP53MAPT
Acetic Acid SCHEMBL10839556 0.54 ALDH1A1 (0.56) STAT5BTP53MAPT
SCHEMBL23161038 0.54 TSHR (0.46) MAPT
SCHEMBL5986436 0.54 TSHR (0.50) MAPT
SCHEMBL22035923 0.54 ALDH1A1 (0.46) STAT5BTP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3305783-A1 NOVEL FURAZAN-3-CARBOXYLIC ACID DERIVATIVES AND USE THEREOF IN TREATMENT OF CANCER Freie Universität Berlin (DE) 2018-04-11 EP disclosed