Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13898921 | 0.89 | FFAR4 (0.49) | TDP1MAPTMAPK1L3MBTL1ALDH1A1 | |
| SCHEMBL4370495 | 0.87 | PDE4A (0.47) | TDP1MAPTMAPK1L3MBTL1PDE4A | |
| SCHEMBL10464043 | 0.80 | S1PR5 (0.48) | PDE4APDE4BPDE4CPDE4DHTR2C | |
| SCHEMBL8768747 | 0.80 | MRGPRX4 (0.51) | MAPTHTR2CHTR2BTSHRRXRA | |
| SCHEMBL7146977 | 0.78 | ELANE (0.47) | ALDH1A1HTR2CHTR2BTSHRHTT | |
| SCHEMBL9574268 | 0.77 | FOLH1 (0.58) | L3MBTL1ALDH1A1APP | |
| SCHEMBL14095898 | 0.77 | PDE4A (0.40) | MAPTL3MBTL1ALDH1A1PDE4APDE4B | |
| SCHEMBL13708416 | 0.76 | PRMT5 (0.47) | L3MBTL1ALDH1A1APPNPC1RAB9A | |
| SCHEMBL14090696 | 0.76 | CYP19A1 (0.46) | MAPK1ALDH1A1PDE4APDE4BPDE4C | |
| SCHEMBL964386 | 0.76 | PRMT5 (0.47) | L3MBTL1ALDH1A1APPNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2705031-B1 | FLASH AND GLOW 1,2-DIOXETANES | LIFE TECHNOLOGIES CORP (US) | 2018-04-11 | — | — | EP | disclosed |