Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | HTR2C | P28335 | 3/20 | 0.43 |
| ▸ | HTR2B | P41595 | 3/20 | 0.43 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768747 | 0.87 | MRGPRX4 (0.51) | TSHRSLC6A4HTR2CHTR2BMAPT | |
| SCHEMBL10464043 | 0.87 | S1PR5 (0.48) | PDE4APDE4BPDE4CPDE4DTSHR | |
| SCHEMBL13898921 | 0.87 | FFAR4 (0.49) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL20041825 | 0.87 | TDP1 (0.45) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL7146977 | 0.84 | ELANE (0.47) | APPTSHRHTR2CHTR2B | |
| SCHEMBL9574268 | 0.83 | FOLH1 (0.58) | APPPRMT5L3MBTL1POLBKMT2A | |
| SCHEMBL14095898 | 0.83 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL15680635 | 0.82 | ALDH1A1 (0.49) | PDE4APDE4BPDE4CPDE4DAPP | |
| SCHEMBL3987261 | 0.81 | PARP1 (0.48) | APPPRMT5L3MBTL1POLBKMT2A | |
| SCHEMBL865598 | 0.81 | POLB (0.54) | MAPTTDP1L3MBTL1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601667-B2 | Ruthenium/iridium complexes; hydrogenation catalysts | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 2009-10-13 | — | — | US | disclosed |
| US-20080234525-A1 | Ruthenium/iridium complexes; hydrogenation catalysts | NAGOYA INDUSTRIAL SCIENCE RESEARCH INSTITUTE (JP) | 2008-09-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080234525-A1 | Ruthenium/iridium complexes; hydrogenation catalysts | ADH5, ADH1A, ADH1C | PDE4A 4793/4885PDE4B 4640/4885PDE4C 4751/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.