SCHEMBL20041892

SCHEMBL20041892

CCCc1ccc(-c2ccc(-c3ccc(C#N)c(F)c3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 18/20 0.51
CYP11B2 P19099 18/20 0.51
TRPV4 Q9HBA0 1/20 0.47
KCNJ1 P48048 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637046 1.00 CYP11B1 (0.51) CYP11B1CYP11B2TRPV4KCNJ1
SCHEMBL29306088 0.93 CYP11B1 (0.46) CYP11B1CYP11B2TRPV4KCNJ1
SCHEMBL8146455 0.92 DAO (0.49) CYP11B1CYP11B2TRPV4KCNJ1
SCHEMBL14526069 0.91 TSHR (0.53) CYP11B1CYP11B2TRPV4KCNJ1
SCHEMBL14526076 0.89 TSHR (0.59) CYP11B1CYP11B2TRPV4KCNJ1
SCHEMBL15783717 0.88 TSHR (0.61) CYP11B1CYP11B2
SCHEMBL3162931 0.88 CYP11B1 (0.49) CYP11B1CYP11B2
SCHEMBL19187744 0.87 CYP11B1 (0.54) CYP11B1CYP11B2TRPV4KCNJ1
SCHEMBL13548285 0.86 TRPV4 (0.53) CYP11B1CYP11B2TRPV4KCNJ1
SCHEMBL10557833 0.86 CYP11B1 (0.48) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114573599-A Photoisomerizable chiral molecules and application thereof in realizing color liquid crystal film patterning 苏州大学 2022-06-03 CN claimed
CN-114573599-A Photoisomerizable chiral molecules and application thereof in realizing color liquid crystal film patterning 苏州大学 2022-06-03 CN disclosed
EP-3022273-B1 LIQUID CRYSTAL POLYMER COMPOSITION, METHOD FOR PREPARING SAME, AND LIQUID CRYSTAL ARTICLE COMPRISING SAME SAINT GOBAIN (FR) 2018-04-11 EP disclosed