Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3971216 | 0.87 | DPP4 (0.51) | DPP4TSHRLMNASMN1; SMN2CYP2C9 | |
| SCHEMBL4487837 | 0.85 | KMT2A (0.60) | DPP4TSHRLMNASMN1; SMN2CYP2C9 | |
| SCHEMBL20041912 | 0.83 | DPP4 (0.65) | DPP4TSHRLMNASMN1; SMN2CYP2C9 | |
| SCHEMBL20248004 | 0.80 | DPP4 (0.85) | DPP4 | |
| SCHEMBL4482398 | 0.79 | DPP4 (0.71) | DPP4TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL20041916 | 0.79 | DPP4 (1.00) | DPP4 | |
| SCHEMBL4469410 | 0.79 | DPP4 (0.55) | DPP4TSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL19315964 | 0.77 | DPP4 (0.45) | DPP4TSHRLMNASMN1; SMN2CYP2C9 | |
| SCHEMBL497449 | 0.77 | DPP4 (0.50) | DPP4TSHRLMNASMN1; SMN2KMT2A | |
| SCHEMBL637987 | 0.76 | DPP4 (0.64) | DPP4TSHRLMNASMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3305787-B1 | XANTHINE DERIVATIVE | JIANGSU TASLY DIYI PHARMACEUTICAL CO LTD (CN) | 2022-02-16 | — | — | EP | disclosed |
| CN-107709324-B | Xanthine derivatives | 江苏天士力帝益药业有限公司 | 2021-06-08 | — | — | CN | disclosed |
| CN-106188058-B | Xanthine derivatives | 江苏天士力帝益药业有限公司 | 2020-11-06 | — | — | CN | disclosed |
| US-20180162860-A1 | XANTHINE DERIVATIVE | JIANGSU TASLY DIYI PHARMACEUTICAL CO., LTD. (CN) | 2018-06-14 | — | — | US | disclosed |
| EP-3305787-A1 | XANTHINE DERIVATIVE | Jiangsu Tasly Diyi Pharmaceutical Co., Ltd. (CN) | 2018-04-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180162860-A1 | XANTHINE DERIVATIVE | XDH, CXCR1, CBR1 | DPP4 1294/4885TSHR 1616/4885LMNA 791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.