Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16305539 | 0.88 | SIGMAR1 (0.34) | HPGDMEN1KMT2ARECQLBCHE | |
| SCHEMBL17984963 | 0.88 | SIGMAR1 (0.34) | HPGDMEN1KMT2ARECQLBCHE | |
| SCHEMBL15994337 | 0.84 | KDM5B (0.45) | HPGDMEN1KMT2ARECQLNPC1 | |
| SCHEMBL15994335 | 0.84 | KDM5B (0.45) | HPGDMEN1KMT2ARECQLNPC1 | |
| SCHEMBL16303334 | 0.81 | KDM5B (0.39) | HPGDMEN1KMT2ARECQLNPC1 | |
| SCHEMBL17984973 | 0.81 | KDM5B (0.39) | HPGDMEN1KMT2ARECQLNPC1 | |
| SCHEMBL16292796 | 0.80 | KDM5B (0.55) | HPGDMEN1KMT2A | |
| SCHEMBL16006901 | 0.80 | KDM5B (0.55) | HPGDMEN1KMT2A | |
| SCHEMBL20041897 | 0.72 | KDM5B (0.43) | HPGDRECQLSMN1; SMN2 | |
| SCHEMBL16305527 | 0.69 | S1PR1 (0.37) | S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2961736-B1 | INHIBITORS OF HISTONE DEMETHYLASES | GILEAD SCIENCES INC (US) | 2018-04-11 | — | — | EP | disclosed |