Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3536740 | 0.95 | ALDH1A1 (0.60) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL13215153 | 0.91 | POLB (0.57) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL1106918 | 0.88 | KMT2A (0.56) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL8865199 | 0.86 | MAPT (0.55) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL18088093 | 0.86 | MAPT (0.54) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3026826 | 0.85 | ALDH1A1 (0.49) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL27456246 | 0.85 | MAPT (0.50) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL3535207 | 0.84 | MAPT (0.60) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL13215131 | 0.84 | POLB (0.52) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 | |
| SCHEMBL4861216 | 0.84 | S1PR4 (0.53) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180098990-A1 | HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098990-A1 | HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | HDAC1, HDAC5, HDAC9 | ALDH1A1 671/4885KMT2A 31/4885MAPT 3211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.