Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 9/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 9/20 | 0.48 |
| ▸ | ABCC1 | P33527 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 7/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042056 | 0.80 | ABCG2 (0.53) | ABCB1ABCG2ABCC1MEN1KMT2A | |
| SCHEMBL29126705 | 0.80 | ABCG2 (0.53) | ABCB1ABCG2ABCC1MEN1KMT2A | |
| SCHEMBL2256504 | 0.78 | ABCG2 (0.73) | ABCB1ABCG2ABCC1MEN1KMT2A | |
| SCHEMBL18088137 | 0.78 | DHFR (0.55) | ABCB1ABCG2ABCC1MEN1KMT2A | |
| SCHEMBL31150159 | 0.75 | ABCG2 (0.54) | ABCB1ABCG2ABCC1 | |
| SCHEMBL29126710 | 0.73 | ABCG2 (0.61) | ABCB1ABCG2ABCC1MEN1KMT2A | |
| SCHEMBL20042294 | 0.73 | MAPT (0.43) | MEN1KMT2AMAPTGAAKDM4E | |
| SCHEMBL3109746 | 0.71 | ABCG2 (0.74) | ABCB1ABCG2ABCC1MEN1KMT2A | |
| SCHEMBL29126698 | 0.71 | CYP1A2 (0.66) | ABCB1ABCG2ABCC1MEN1KMT2A | |
| SCHEMBL2256420 | 0.70 | POLB (0.67) | ABCB1ABCG2ABCC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180098990-A1 | HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | GUANGDONG ZHONGSHENG PHARMACEUTICAL CO., LTD (CN) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098990-A1 | HISTONE DEACETYLASE INHIBITOR, AND PREPARATION METHOD AND USE THEREOF | HDAC1, HDAC5, HDAC9 | ABCB1 1390/4885ABCG2 198/4885ABCC1 2038/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.