Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.33 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | USP1 | O94782 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21715828 | 0.92 | DDR1 (0.33) | GRIN1GRIN2BDDR1QRFPRCNR2 | |
| SCHEMBL20042495 | 0.90 | RORC (0.36) | GRIN1GRIN2BDDR1QRFPRCNR2 | |
| SCHEMBL31534723 | 0.87 | NPC1 (0.34) | GRIN1GRIN2BDDR1QRFPRCNR2 | |
| SCHEMBL18013268 | 0.87 | NPC1 (0.34) | GRIN1GRIN2BDDR1QRFPRCNR2 | |
| SCHEMBL21999928 | 0.85 | DDR1 (0.32) | DDR1 | |
| SCHEMBL20042497 | 0.84 | DDR1 (0.34) | GRIN1GRIN2BDDR1QRFPRCNR2 | |
| SCHEMBL17967743 | 0.83 | DHODH (0.35) | DDR1QRFPRCNR2RORCNPC1 | |
| SCHEMBL31534712 | 0.83 | DHODH (0.35) | DDR1QRFPRCNR2RORCNPC1 | |
| SCHEMBL17967726 | 0.83 | CNR2 (0.35) | DDR1CNR2RORCNPC1RAB9A | |
| SCHEMBL18013264 | 0.83 | CNR2 (0.35) | DDR1CNR2RORCNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2022-05-24 | — | — | US | disclosed |
| EP-3523299-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AG (DE) | 2021-04-14 | — | — | EP | disclosed |
| US-20200048246-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-02-13 | — | — | US | disclosed |
| WO-2018065292-A1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLE DERIVATIVES AS PEST CONTROL AGENTS | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200048246-A1 | 2-(HET)ARYL-SUBSTITUTED FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | EPHX2, CYP8B1, CYP1B1 | GRIN1 1470/4885GRIN2B 1786/4885DDR1 2668/4885 |
| US-11339155-B2 | 2-(het)aryl-substituted fused bicyclic heterocycle derivatives as pesticides | EPHX2, CYP8B1, CYP1B1 | GRIN1 1470/4885GRIN2B 1786/4885DDR1 2668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.