SCHEMBL20042468

SCHEMBL20042468

Cc1ccc2c(c1)C(=O)CC2=C(C#N)C#N

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.41
▸ MAPT P10636 2/20 0.41
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA4 P22748 1/20 0.39
▸ CA7 P43166 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ MAOA P21397 1/20 0.38
▸ MAOB P27338 1/20 0.38
▸ USP8 P40818 1/20 0.38
▸ USP7 Q93009 1/20 0.38
▸ ATM Q13315 2/20 0.37
▸ ALDH1A1 P00352 2/20 0.37
▸ MEN1 O00255 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ HTT P42858 1/20 0.37
▸ KMT2A Q03164 1/20 0.37
▸ ELANE P08246 1/20 0.37
▸ METAP1 P53582 2/20 0.36
▸ RAD52 P43351 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30464045 0.94 KDM4E (0.41) KDM4EMAPTCA1CA2CA4
SCHEMBL7048653 0.94 KDM4E (0.41) KDM4EMAPTCA1CA2CA4
SCHEMBL7045045 0.86 MAPT (0.39) KDM4EMAPTCA1CA2CA4
SCHEMBL21795579 0.81 EGFR (0.35) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL23515574 0.81 EGFR (0.39) EGFR
SCHEMBL21851280 0.81 S100A4 (0.40) KDM4EUSP8USP7HPGDMETAP1
SCHEMBL21795577 0.81 CA1 (0.39) MAPTCA1CA2CA7CA9
SCHEMBL20819745 0.81 S100A4 (0.40) MAPTCA1CA2CA4CA7
SCHEMBL31023251 0.81 S100A4 (0.40) MAPTCA1CA2CA4CA7
SCHEMBL30632305 0.81 CA1 (0.39) MAPTCA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109791987-B Organic semiconductor compound 天光材料科技股份有限公司 2023-10-24 — — CN disclosed
CN-109804481-B Organic photodetector 天光材料科技股份有限公司 2023-09-29 — — CN disclosed
EP-3523308-B1 ORGANIC SEMICONDUCTING COMPOUNDS RAYNERGY TEK INC (TW) 2023-09-06 — — EP disclosed
EP-3620458-B1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-07-05 — — EP disclosed
CN-109790176-B Organic semiconductor compound 天光材料科技股份有限公司 2023-06-02 — — CN disclosed
US-11649321-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2023-05-16 — — US disclosed
CN-111418079-B Aromatic systems based on fused ring thiophenes 香港科技大学 2023-05-16 — — CN disclosed
US-11637246-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2023-04-25 — — US disclosed
US-11196005-B2 Organic semiconducting compounds Raynergy Tek Incorporation (TW) 2021-12-07 — — US disclosed
US-11183637-B2 Organic photodetector Raynergy Tek Incorporation (TW) 2021-11-23 — — US disclosed
US-20200388769-A1 ORGANIC SEMICONDUCTING COMPOUNDS Raynergy Tek Incorporation (TW) 2020-12-10 — — US disclosed
US-20200251661-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2020-08-06 — — US disclosed
CN-111418079-A Aromatic systems based on condensed ring thiophenes 香港科技大学 2020-07-14 — — CN disclosed
EP-3620458-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2020-03-11 — — EP disclosed
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2020-02-13 — — US disclosed
US-20200052216-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2020-02-13 — — US disclosed
US-20190237672-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2019-08-01 — — US disclosed
WO-2018065352-A1 ORGANIC PHOTODETECTOR MERCK PATENT GMBH (DE) 2018-04-12 — — WO disclosed
WO-2018065356-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 — — WO disclosed
WO-2018065350-A1 ORGANIC SEMICONDUCTING COMPOUNDS MERCK PATENT GMBH (DE) 2018-04-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200052227-A1 ORGANIC SEMICONDUCTING COMPOUNDS OCIAD2, OCIAD1, OSTC KDM4E 704/4885MAPT 32/4885CA1 2638/4885
US-20200251661-A1 HETEROCYCLIC COMPOUND AND ORGANIC ELECTRONIC DEVICE COMPRISING SAME ODC1, OR10J3, CYP1A1 KDM4E 954/4885MAPT 3296/4885CA1 1902/4885
US-11649321-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC KDM4E 704/4885MAPT 32/4885CA1 2638/4885
US-20200388769-A1 ORGANIC SEMICONDUCTING COMPOUNDS OCIAD2, OCIAD1, OSTC KDM4E 704/4885MAPT 32/4885CA1 2638/4885
US-11637246-B2 Organic semiconducting compounds OCIAD2, OCIAD1, OSTC KDM4E 704/4885MAPT 32/4885CA1 2638/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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