Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042682 | 1.00 | NPY5R (0.34) | NPY5RALDH1A1SMN1; SMN2GAAGUSB | |
| SCHEMBL20042683 | 0.74 | NPY5R (0.39) | NPY5RSMN1; SMN2MEN1KMT2A | |
| SCHEMBL31614818 | 0.74 | NPY5R (0.39) | NPY5RSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31614730 | 0.73 | MEN1 (0.39) | NPY5RSMN1; SMN2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31405518 | 0.73 | MEN1 (0.39) | NPY5RSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22727886 | 0.71 | MTOR (0.47) | NPY5RALDH1A1MAPT | |
| SCHEMBL15859967 | 0.68 | — | — | |
| SCHEMBL442259 | 0.67 | MTOR (0.44) | — | |
| SCHEMBL17297899 | 0.67 | HTR2A (0.33) | — | |
| SCHEMBL20042661 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |