Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 12/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.33 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31614818 | 1.00 | NPY5R (0.39) | NPY5RMAPK1HSD17B10L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL31614730 | 0.98 | MEN1 (0.39) | NPY5RMAPK1HSD17B10L3MBTL1MEN1 | |
| Hydrochloric Acid SCHEMBL31405518 | 0.98 | MEN1 (0.39) | NPY5RMAPK1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL22727886 | 0.85 | MTOR (0.47) | NPY5RMAPK1HSD17B10MTORMAP2K7 | |
| SCHEMBL4480611 | 0.81 | NPY5R (0.41) | NPY5RMAPK1HSD17B10L3MBTL1MEN1 | |
| SCHEMBL20042881 | 0.81 | HRH1 (0.41) | HSD17B10L3MBTL1MTORSMN1; SMN2PDE4A | |
| SCHEMBL20042777 | 0.79 | HRH4 (0.38) | NPY5R | |
| SCHEMBL20042813 | 0.79 | HTR2C (0.37) | MTORSMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL20042692 | 0.79 | MTOR (0.37) | NPY5RHSD17B10L3MBTL1MEN1KMT2A | |
| SCHEMBL31615106 | 0.79 | MTOR (0.37) | NPY5RHSD17B10L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |