Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 3/20 | 0.46 |
| ▸ | CKS1B | P61024 | 2/20 | 0.39 |
| ▸ | SKP1 | P63208 | 2/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042712 | 0.88 | MTOR (0.47) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL20042972 | 0.85 | MTOR (0.47) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL20042670 | 0.85 | MTOR (0.47) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL31614795 | 0.85 | MTOR (0.47) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL31516224 | 0.84 | MTOR (0.46) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL20042815 | 0.84 | MTOR (0.46) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL31614769 | 0.82 | MTOR (0.49) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL20042672 | 0.82 | MTOR (0.49) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL20042808 | 0.82 | MTOR (0.47) | MTORCKS1BSKP1SKP2PARP1 | |
| SCHEMBL19358163 | 0.82 | MTOR (0.46) | MTORCKS1BSKP1SKP2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |