Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.36 |
| ▸ | SKP1 | P63208 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | RAF1 | P04049 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20042708 | 0.88 | MTOR (0.46) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL20042972 | 0.83 | MTOR (0.47) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL31614795 | 0.83 | MTOR (0.47) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL20042670 | 0.83 | MTOR (0.47) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL31516224 | 0.82 | MTOR (0.46) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL20042815 | 0.82 | MTOR (0.46) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL31516232 | 0.82 | MTOR (0.47) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL23441624 | 0.81 | NR1H2 (0.39) | MTORNR1H2PARP1TNKS2PARP2 | |
| SCHEMBL20042818 | 0.81 | MTOR (0.46) | MTORPARP1TNKS2PARP2CKS1B | |
| SCHEMBL20042672 | 0.81 | MTOR (0.49) | MTORPARP1TNKS2PARP2CKS1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018066718-A1 | THERAPEUTIC COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-04-12 | — | — | WO | disclosed |