⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28425745 | 1.00 | — | — | |
| SCHEMBL17002465 | 0.97 | CYP2D6 (0.41) | — | |
| SCHEMBL17002464 | 0.97 | CYP2D6 (0.41) | — | |
| SCHEMBL15630429 | 0.97 | CYP2D6 (0.41) | — | |
| SCHEMBL15594589 | 0.97 | CYP2D6 (0.41) | — | |
| SCHEMBL28071825 | 0.97 | — | — | |
| SCHEMBL6826526 | 0.90 | — | — | |
| SCHEMBL5682444 | 0.67 | L3MBTL1 (0.38) | — | |
| SCHEMBL10622966 | 0.65 | L3MBTL1 (0.36) | — | |
| SCHEMBL69143 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109232531-B | Preparation method of cabitinib | 安庆奇创药业有限公司 | 2020-06-16 | — | — | CN | claimed |
| CN-106045969-B | A kind of synthetic method of the card than replacing Buddhist nun | 湖南欧亚药业有限公司 | 2019-04-12 | — | — | CN | claimed |
| CN-106045969-A | Synthesis method of cobimetinib | 湖南欧亚生物有限公司 | 2016-10-26 | — | — | CN | claimed |
| US-12577373-B2 | Carbodiimide composition, curing agent composition, coating composition and resin cured product | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2026-03-17 | — | — | US | disclosed |
| CN-114516830-B | Preparation method and application of risedronic acid | 兰州优莱特化学科技有限公司 | 2023-12-19 | — | — | CN | disclosed |
| US-20230135772-A1 | CARBODIIMIDE COMPOSITION, CURING AGENT COMPOSITION, COATING COMPOSITION AND RESIN CURED PRODUCT | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2023-05-04 | — | — | US | disclosed |
| EP-4130154-A1 | CARBODIIMIDE COMPOSITION, HARDENER COMPOSITION, COATING COMPOSITION, AND CURED RESIN OBJECT | Asahi Kasei Kabushiki Kaisha (JP) | 2023-02-08 | — | — | EP | disclosed |
| CN-115190901-A | Carbodiimide composition, curing agent composition, coating composition, and resin cured product | 旭化成株式会社 | 2022-10-14 | — | — | CN | disclosed |
| CN-111808101-B | Application of gamma-carboline hydroxamic acid anti-tumor metastasis compound and preparation method thereof | 济南大学 | 2022-05-24 | — | — | CN | disclosed |
| CN-114516830-A | Preparation method and application of letidronic acid | 兰州优莱特化学科技有限公司 | 2022-05-20 | — | — | CN | disclosed |
| CN-109232531-B | Preparation method of cabitinib | 安庆奇创药业有限公司 | 2020-06-16 | — | — | CN | disclosed |
| WO-2008112280-A1 | SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS | INTRA-CELLULAR THERAPIES, INC. (US) | 2008-09-18 | — | — | WO | disclosed |
| US-20080177014-A1 | Polymerization Catalyst Composition and Process for Production of Polymer | MITSUI CHEMICALS, INC. (JP) | 2008-07-24 | — | — | US | disclosed |
| US-7371746-B2 | 1,2,4-Thiadiazole compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2008-05-13 | — | — | US | disclosed |
| CN-101128491-A | Polymerization catalyst composition and method for producing polymer | MITSUI CHEMICALS INC (JP) | 2008-02-20 | — | — | CN | disclosed |
| EP-1857471-A1 | POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER | Mitsui Chemicals, Inc. (JP) | 2007-11-21 | — | — | EP | disclosed |
| EP-1765798-A2 | 1,2,4- THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| WO-2006014287-A1 | HUMAN GLUCAGON-LIKE-PEPTIDE-1 MODULATORS AND THEIR USE IN THE TREATMENT OF DIABETES AND RELATED CONDITIONS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-02-09 | — | — | WO | disclosed |
| WO-2005037805-A2 | 1,2,4-THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | WO | disclosed |