SCHEMBL20044980

SCHEMBL20044980

CCCCCCc1cccc2c1ccc1c3cc(C#C[Si](C(C)C)(C(C)C)C(C)C)c4c5ccccc5ccc4c3cc(C#C[Si](C(C)C)(C(C)C)C(C)C)c21

nearest known ligand 0.38

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TLR8 Q9NR97 8/20 0.36
SIGMAR1 Q99720 1/20 0.33
MTNR1A P48039 2/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
USP2 O75604 1/20 0.33
ALDH1A1 P00352 1/20 0.33
GLA P06280 1/20 0.33
CYP3A4 P08684 1/20 0.33
GAA P10253 1/20 0.33
HPGD P15428 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
HSD17B10 Q99714 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
BCHE P06276 1/20 0.32
KCNH2 Q12809 1/20 0.32
MC4R P32245 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20044993 0.88 TLR8 (0.35) TLR8LIPGKCNH2
SCHEMBL20044986 0.80 TLR8 (0.30) TLR8
SCHEMBL16666257 0.74 LIPG (0.49) TLR8MAPTKDM4EALDH1A1GLA
SCHEMBL28339808 0.74 LIPG (0.49) TLR8MAPTKDM4EALDH1A1GLA
SCHEMBL2577637 0.74 LIPG (0.49) TLR8MAPTKDM4EALDH1A1GLA
SCHEMBL9764124 0.74 LIPG (0.49) TLR8MAPTKDM4EALDH1A1GLA
SCHEMBL9621111 0.74 LIPG (0.49) TLR8MAPTKDM4EALDH1A1GLA
SCHEMBL28452662 0.74 LIPG (0.49) TLR8MAPTKDM4EALDH1A1GLA
SCHEMBL4716555 0.73 CYP1A2 (0.41) TLR8MTNR1AMAPTALDH1A1HPGD
SCHEMBL1023164 0.72 HPRT1 (0.48) TLR8MAPTKDM4EALDH1A1GLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180102222-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL USING THE SAME FUJIFILM CORPORATION (JP) 2018-04-12 US disclosed
US-20180102222-A1 PHOTOELECTRIC CONVERSION ELEMENT, AND SOLAR CELL USING THE SAME FUJIFILM CORPORATION (JP) 2018-04-12 US disclosed