SCHEMBL20045038

SCHEMBL20045038

CC(F)(F)S(=O)(=O)NCF

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA7 P43166 1/20 0.30
CA13 Q8N1Q1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25008100 0.79 EPHX1 (0.39) EPHX1CA1CA2CA7CA13
SCHEMBL25438475 0.74 CA1 (0.38) EPHX1CA1CA2CA7CA13
SCHEMBL777551 0.73 CA12 (0.35) EPHX1CA1CA2CA7
SCHEMBL243798 0.71 PTPN11 (0.37) EPHX1CA1CA2CA7CA13
SCHEMBL14713537 0.70 CA2 (0.32) CA1CA2
SCHEMBL12891809 0.69 EPHX1 (0.75) EPHX1CA1CA2CA7
SCHEMBL4461436 0.69
SCHEMBL9608579 0.69
SCHEMBL12884415 0.69 GRIA4 (0.31) CA1CA2
SCHEMBL12256400 0.66 CA12 (0.57) CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11822245-B2 Resist composition and pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2023-11-21 US disclosed
US-20180099928-A1 SULFONIUM COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180099928-A1 SULFONIUM COMPOUND, RESIST COMPOSITION, AND PATTERN FORMING PROCESS C1R, LBR, SMARCC2 EPHX1 4388/4885CA1 1679/4885CA2 1377/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.