Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | SCN1A | P35498 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21983627 | 0.81 | HRH4 (0.40) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL7778093 | 0.80 | ADH1B (0.39) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL22296080 | 0.80 | ADH1B (0.32) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL13157917 | 0.79 | MEN1 (0.33) | ANPEP | |
| SCHEMBL22297371 | 0.78 | ACE2 (0.38) | ANPEP | |
| SCHEMBL18244860 | 0.78 | ADH1B (0.38) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL20325500 | 0.77 | SCN1A (0.34) | SCN1ASCN2ASCN3A | |
| SCHEMBL1005943 | 0.76 | ADH1B (0.45) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL23189474 | 0.76 | ADH1B (0.36) | ADH1BADH1CADH1AALDH1A1CYP1A2 | |
| SCHEMBL20193833 | 0.76 | CYP2C19 (0.41) | CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067615-A1 | COMPOUNDS, DEVICES, AND USES THEREOF | SIGILON THERAPEUTICS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |