SCHEMBL20047058

SCHEMBL20047058

C#CCOC1CCOCC1

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CHRM2 P08172 1/20 0.37
CHRM4 P08173 1/20 0.37
CHRM5 P08912 1/20 0.37
CHRM1 P11229 1/20 0.37
CHRM3 P20309 1/20 0.37
SPHK1 Q9NYA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5919142 0.87
SCHEMBL27430861 0.83
SCHEMBL1513752 0.78
SCHEMBL120964 0.78
SCHEMBL2005416 0.77 ELANE (0.32) SPHK1
SCHEMBL5737479 0.76 NPC1 (0.40) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL20857076 0.76
SCHEMBL604277 0.74 CHRM2 (0.33) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL24334485 0.73 CHRM2 (0.37) CHRM2CHRM4CHRM5CHRM1CHRM3
SCHEMBL22856593 0.73 SLC6A2 (0.39) CHRM2CHRM4CHRM5CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260109677-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS INC (US) 2026-04-23 US disclosed
US-12522571-B2 Compounds, devices, and uses thereof SIGILON THERAPEUTICS, INC. (US) 2026-01-13 US disclosed
US-20250281672-A1 IDENTIFICATION OF PRO- AND ANTI-INFLAMMATORY LIPIDS RELATING TO IMMUNE RESPONSE TO MEDICAL IMPLANTS WILLIAM MARSH RICE UNIVERSITY (US) 2025-09-11 US disclosed
WO-2024245193-A1 HETEROAROMATIC RING COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF 上海艾力斯医药科技股份有限公司 2024-12-05 WO disclosed
US-20240279187-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. 2024-08-22 US disclosed
US-11945786-B2 Compounds, devices, and uses thereof SIGILON THERAPEUTICS, INC. (US) 2024-04-02 US disclosed
WO-2023010117-A1 IDENTIFICATION OF PRO- AND ANTI-INFLAMMATORY LIPIDS RELATING TO IMMUNE RESPONSE TO MEDICAL IMPLANTS WILLIAM MARSH RICE UNIVERSITY (US) 2023-02-02 WO disclosed
US-20200039943-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. 2020-02-06 US disclosed
US-20200039943-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. 2020-02-06 US disclosed
WO-2018067615-A1 COMPOUNDS, DEVICES, AND USES THEREOF SIGILON THERAPEUTICS, INC. (US) 2018-04-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200039943-A1 COMPOUNDS, DEVICES, AND USES THEREOF SLC10A1, SLCO1B3, SLC5A1 CHRM2 964/4885CHRM4 1145/4885CHRM5 754/4885
US-11945786-B2 Compounds, devices, and uses thereof SLC10A1, SLCO1B3, SLC5A1 CHRM2 964/4885CHRM4 1145/4885CHRM5 754/4885
US-20240279187-A1 COMPOUNDS, DEVICES, AND USES THEREOF SLC10A1, SLCO1B3, SLC5A1 CHRM2 964/4885CHRM4 1145/4885CHRM5 754/4885
US-20260109677-A1 COMPOUNDS, DEVICES, AND USES THEREOF NR3C2, AGTR1, CHRM1 CHRM2 20/4885CHRM4 178/4885CHRM5 82/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.