SCHEMBL2004728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2005842	0.91	ERN1 (0.41)	MAPK14ERN1MRGPRX4S1PR5PTGER1
	SCHEMBL2007056	0.88	MAPK14 (0.47)	MAPK14MRGPRX4S1PR5GRM1PTGER1
	SCHEMBL2003916	0.84	S1PR5 (0.40)	MAPK14ERN1MRGPRX4S1PR5PTGER1
	SCHEMBL2006708	0.84	MRGPRX4 (0.40)	MAPK14ERN1MRGPRX4S1PR5PTGER1
	SCHEMBL2006258	0.83	NR3C1 (0.41)	MAPK14MRGPRX4S1PR5PTGER1CCR1
	SCHEMBL2008499	0.82	MAPK14 (0.46)	MAPK14ERN1MRGPRX4S1PR5PTGER1
	SCHEMBL2004763	0.81	S1PR5 (0.39)	MAPK14ERN1MRGPRX4S1PR5MAPT
	SCHEMBL14085312	0.80	CYP11B1 (0.42)	MAPK14MRGPRX4S1PR5RXFP1MAPT
	SCHEMBL2003613	0.80	MAPK14 (0.44)	MAPK14MRGPRX4S1PR5PTGER1CCR1
	SCHEMBL2013480	0.80	MRGPRX4 (0.40)	MAPK14ERN1MRGPRX4S1PR5PTGER1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.