Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 20/20 | 0.54 |
| ▸ | PGR | P06401 | 10/20 | 0.54 |
| ▸ | AR | P10275 | 9/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21169759 | 0.95 | NR3C1 (0.55) | NR3C1PGRARCYP3A4 | |
| SCHEMBL20048085 | 0.87 | NR3C1 (0.73) | NR3C1PGRARCYP3A4 | |
| SCHEMBL20048202 | 0.83 | NR3C1 (0.55) | NR3C1PGRARCYP3A4 | |
| SCHEMBL22903769 | 0.83 | NR3C1 (0.66) | NR3C1PGRARCYP3A4 | |
| SCHEMBL20048082 | 0.82 | NR3C1 (0.73) | NR3C1PGRARCYP3A4 | |
| SCHEMBL22903824 | 0.82 | NR3C1 (0.76) | NR3C1PGRARCYP3A4 | |
| SCHEMBL21729671 | 0.82 | NR3C1 (0.68) | NR3C1PGRARCYP3A4 | |
| SCHEMBL22903833 | 0.81 | NR3C1 (0.52) | NR3C1PGRARCYP3A4 | |
| SCHEMBL21470274 | 0.81 | NR3C1 (0.77) | NR3C1PGRARCYP3A4 | |
| SCHEMBL21470349 | 0.81 | NR3C1 (0.61) | NR3C1PGRARCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018068021-A1 | INHIBITORS OF GLUCOCORTICOID RECEPTOR | ORIC PHARMACEUTICALS, INC. (US) | 2018-04-12 | — | — | WO | disclosed |