⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498202 | 1.00 | — | — | |
| Benzene SCHEMBL21643167 | 1.00 | TSHR (0.35) | — | |
| Benzene SCHEMBL21643168 | 1.00 | TSHR (0.35) | — | |
| SCHEMBL20048651 | 1.00 | — | — | |
| SCHEMBL30306603 | 1.00 | — | — | |
| Piperazine SCHEMBL11076913 | 0.85 | HTR2C (0.36) | — | |
| SCHEMBL23569386 | 0.78 | MAOA (0.46) | — | |
| SCHEMBL20048800 | 0.78 | MAOA (0.46) | — | |
| SCHEMBL7451492 | 0.75 | CYP3A4 (0.33) | — | |
| SCHEMBL31303933 | 0.73 | MAOB (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11802110-B2 | 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase | Oxford Drug Design Limited (GB) | 2023-10-31 | — | — | US | disclosed |
| US-11802110-B2 | 2-amino-N-(arylsulfinyl)-acetamide compounds as inhibitors of bacterial aminoacyl-tRNA synthetase | Oxford Drug Design Limited (GB) | 2023-10-31 | — | — | US | disclosed |
| US-20200039929-A1 | 2-AMINO-N-(ARYLSULFINYL)-ACETAMIDE COMPOUNDS AS INHIBITORS OF BACTERIAL AMINOACYL-TRNA SYNTHETASE | INHIBOX LIMITED (GB) | 2020-02-06 | — | — | US | disclosed |
| WO-2018065611-A1 | 2-AMINO-N-(ARYLSULFINYL)-ACETAMIDE COMPOUNDS AS INHIBITORS OF BACTERIAL AMINOACYL-TRNA SYNTHETASE | Oxford Drug Design Limited (GB) | 2018-04-12 | — | — | WO | disclosed |
| CN-100575338-C | Compound of optically pure sulfenamides and application thereof | CHENGDU BIOLOGY RES INST OF THE CHINESE ACADEMY OF SCIENCES | 2009-12-30 | — | — | CN | disclosed |
| CN-1927830-A | Compound of optically pure sulfenamides and application thereof | CHENGDU BIOLOGY RES INST OF TH (CN) | 2007-03-14 | — | — | CN | disclosed |