Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 4/20 | 0.48 |
| ▸ | CES1 | P23141 | 4/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | PPARD | Q03181 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 6/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | TLR2 | O60603 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | FABP4 | P15090 | 2/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18971148 | 0.98 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL11171037 | 0.98 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL6894821 | 0.93 | — | — | |
| SCHEMBL23027742 | 0.87 | HRH3 (0.58) | FAAHMEN1KMT2APPARGPPARD | |
| SCHEMBL18971161 | 0.87 | HRH3 (0.58) | FAAHMEN1KMT2APPARGPPARD | |
| SCHEMBL27684077 | 0.80 | HSP90AA1 (0.59) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL6063048 | 0.80 | HSP90AA1 (0.54) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| Bicarbonate SCHEMBL28928937 | 0.79 | HSP90AA1 (0.48) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL25544720 | 0.78 | HDAC3 (0.39) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL9860468 | 0.77 | HSP90AA1 (0.55) | HSP90AA1FAAHMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018067702-A1 | BOTTLEBRUSH COPOLYMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2018-04-12 | — | — | WO | disclosed |