Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | FAAH | O00519 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.45 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 5/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TLR2 | O60603 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | FABP4 | P15090 | 2/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14166466 | 1.00 | HSP90AA1 (0.55) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL14166875 | 0.96 | HSP90AA1 (0.50) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL19041099 | 0.91 | HSP90AA1 (0.47) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL10909077 | 0.89 | SLC6A5 (0.51) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL10909147 | 0.89 | HSP90AA1 (0.52) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL10911251 | 0.87 | GPR84 (0.55) | MEN1KMT2APPARGPPARDPPARA | |
| SCHEMBL11704315 | 0.84 | CES2 (0.42) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL10909670 | 0.84 | HSP90AA1 (0.47) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL10912801 | 0.84 | DNM1 (0.58) | HSP90AA1FAAHMEN1KMT2AMAPK1 | |
| SCHEMBL6063048 | 0.83 | HSP90AA1 (0.54) | HSP90AA1FAAHMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0418071-A2 | New N-aryl and N-heteroarylamide and urea derivatives as inhibitors of acyl coenzyme A: cholesterol acyl transferase | PFIZER INC. (US) | 1991-03-20 | — | — | EP | disclosed |