Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL9129677 | 0.99 | MAPT (0.41) | MAPTTHRBRECQLALDH1A1HPGD | |
| Betaine SCHEMBL5676650 | 0.90 | CYP2D6 (0.36) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL7250099 | 0.88 | MAPT (0.56) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL13646792 | 0.80 | MAPT (0.41) | MAPTTHRBRECQLALDH1A1HPGD | |
| Water SCHEMBL10949547 | 0.78 | MAPT (0.33) | MAPTTHRBRECQLALDH1A1KDM4E | |
| SCHEMBL3191322 | 0.77 | HSD17B10 (0.59) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL4830357 | 0.76 | KDM4E (0.55) | MAPTALDH1A1KDM4EPOLBHSD17B10 | |
| Water SCHEMBL1044054 | 0.76 | HSD17B10 (0.58) | MAPTTHRBRECQLALDH1A1HPGD | |
| SCHEMBL12376758 | 0.75 | ITGB2 (0.33) | MAPTHPGDITGB2ITGAM | |
| SCHEMBL6556048 | 0.73 | HSD17B10 (0.58) | MAPTTHRBRECQLALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | claimed |
| US-7960181-B2 | Chromoionophore and method of determining potassium ions | OPTI MEDICAL SYSTEMS (US) | 2011-06-14 | — | — | US | disclosed |
| US-7858383-B2 | Chromoionophore and method of determining sodium ions | OPTI MEDICAL SYSTEMS (US) | 2010-12-28 | — | — | US | disclosed |
| EP-1627635-B1 | Benzothiazolium compounds for use in methods of inhibiting NO production and TNF alpha and treating coronaviral infection | NAT HEALTH RESEARCH INSTITUTES (TW) | 2009-10-07 | — | — | EP | disclosed |
| WO-2007131042-A2 | CHROMOIONOPHORE AND METHOD OF DETERMINING POTASSIUM IONS | OPTI MEDICAL SYSTEMS, INC (US) | 2007-11-15 | — | — | WO | disclosed |
| WO-2007131054-A2 | CHROMOIONOPHORE AND METHOD OF DETERMINING SODIUM IONS | OPTI MEDICAL SYSTEMS (US) | 2007-11-15 | — | — | WO | disclosed |
| US-20070259443-A1 | CHROMOIONOPHORE AND METHOD OF DETERMINING POTASSIUM IONS | OPTI MEDICAL SYSTEMS, INC. | 2007-11-08 | — | — | US | disclosed |
| US-20070259444-A1 | ions are contacted with a compound having chromophoric and ionophoric moieties; the ionophoric moiety interacts with the ions present resulting in the chromophoric moiety changing its radiation absorption properties in the ultraviolet and visible regions of the spectrum; whole blood, plasma, serum, urine | OPTI MEDICAL SYSTEMS, INC. | 2007-11-08 | — | — | US | disclosed |
| EP-1200051-B1 | AGENT FOR DYING KERATIN FIBERS | HENKEL KGAA (DE) | 2006-02-01 | — | — | EP | disclosed |