Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 10/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191322 | 0.96 | HSD17B10 (0.59) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| Water SCHEMBL1044054 | 0.94 | HSD17B10 (0.58) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| SCHEMBL16865132 | 0.85 | MAPT (0.71) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| SCHEMBL3191317 | 0.82 | MAPT (0.74) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| SCHEMBL9156344 | 0.81 | MAPT (0.77) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| SCHEMBL18655696 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1HPGDPOLBTHRB | |
| SCHEMBL10747902 | 0.81 | HSD17B10 (0.61) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| SCHEMBL13172599 | 0.80 | MAPT (0.55) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| Water SCHEMBL10952583 | 0.80 | MAPT (0.57) | HSD17B10CYP2D6TSHRMAPTALDH1A1 | |
| SCHEMBL2906835 | 0.79 | HSD17B10 (0.63) | HSD17B10CYP2D6TSHRMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013114115-A1 | PROCESS FOR DYE PRODUCTION | UNIVERSITY OF CENTRAL LANCASHIRE (GB) | 2013-08-08 | — | — | WO | disclosed |
| US-7842811-B2 | Cyanine dye compounds | Life Technologies Corporation (US) | 2010-11-30 | — | — | US | disclosed |
| US-7737281-B2 | Purine based fluorescent dyes | ENZO LIFE SCIENCES, INC. C/O ENZO BIOCHEM, INC. (US) | 2010-06-15 | — | — | US | disclosed |
| US-20100120051-A1 | CYANINE DYE COMPOUNDS | Life Technologies Corporation (US) | 2010-05-13 | — | — | US | disclosed |
| US-7655409-B2 | Have negatively charged substituent for fluorescent staining of DNA; used to distinguish DNA present in a sample from RNA | Life Technologies Corporation (US) | 2010-02-02 | — | — | US | disclosed |
| US-20090047683-A1 | CYANINE DYE COMPOUNDS | INVITROGEN CORPORATION (US) | 2009-02-19 | — | — | US | disclosed |
| US-7446202-B2 | Cyanine dye compounds | MOLECULAR PROBES, INC. (US) | 2008-11-04 | — | — | US | disclosed |
| EP-1394219-A1 | PH sensitive cyanine dyes as reactive fluorescent reagents | CARNEGIE-MELLON UNIVERSITY (US) | 2004-03-03 | — | — | EP | disclosed |
| WO-2000075237-A9 | pH SENSITIVE CYANINE DYES AS REACTIVE FLUORESCENT REAGENTS | UNIV CARNEGIE MELLON (US) | 2002-05-10 | — | — | WO | disclosed |