Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580317 | 0.76 | PPARA (0.41) | EGFRSYK | |
| SCHEMBL15956011 | 0.76 | PPARA (0.41) | EGFRSYK | |
| SCHEMBL20050106 | 0.76 | SYK (0.39) | EGFRSYK | |
| SCHEMBL3577414 | 0.71 | CACNA1B (0.47) | EGFRSYK | |
| SCHEMBL31398897 | 0.67 | PPARA (0.41) | EGFRSYK | |
| SCHEMBL31398893 | 0.65 | TRPA1 (0.38) | EGFRSYK | |
| SCHEMBL21591579 | 0.64 | STK17B (0.60) | — | |
| SCHEMBL30132335 | 0.64 | STK17B (0.60) | — | |
| SCHEMBL31398957 | 0.63 | SYK (0.43) | EGFRSYK | |
| SCHEMBL31398924 | 0.63 | SYK (0.43) | EGFRSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180098998-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2018-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180098998-A1 | HETEROCYCLIC AMIDES AS KINASE INHIBITORS | CNKSR1, ARAF, MAP4K2 | EGFR 478/4885SYK 428/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.