Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 16/20 | 1.00 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.88 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.62 |
| ▸ | OTUD7B | Q6GQQ9 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23198226 | 1.00 | USP30 (1.00) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL23198203 | 1.00 | USP30 (1.00) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL17632033 | 0.94 | UCHL1 (1.00) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL17632038 | 0.94 | UCHL1 (1.00) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL23403455 | 0.87 | UCHL1 (0.87) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL17632208 | 0.87 | UCHL1 (0.87) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL17632501 | 0.85 | UCHL1 (0.83) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL29992744 | 0.85 | UCHL1 (0.83) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL17631603 | 0.84 | UCHL1 (0.83) | USP30UCHL1MKNK1OTUD7B | |
| SCHEMBL17631683 | 0.84 | UCHL1 (0.83) | USP30UCHL1MKNK1OTUD7B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109803963-B | Cyano-substituted heterocycles having USP30 inhibitor activity | 特殊治疗有限公司 | 2022-04-26 | — | — | CN | claimed |
| CN-109803963-B | Cyano-substituted heterocycles having USP30 inhibitor activity | 特殊治疗有限公司 | 2022-04-26 | — | — | CN | disclosed |
| EP-3523291-B1 | CYANO-SUBSTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 | MISSION THERAPEUTICS LTD (GB) | 2021-04-14 | — | — | EP | disclosed |
| WO-2018065768-A1 | CYANO-SUBSTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30 | MISSION THERAPEUTICS LIMITED (GB) | 2018-04-12 | — | — | WO | disclosed |