Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DUT | P33316 | 7/20 | 0.34 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.33 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.33 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.33 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20407952 | 1.00 | POLB (0.55) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL14143203 | 0.92 | POLB (0.47) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL25711972 | 0.90 | POLB (0.46) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL13896528 | 0.90 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL5669639 | 0.85 | POLB (0.67) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL23710654 | 0.85 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL19303349 | 0.85 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL13471838 | 0.85 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL26781635 | 0.84 | POLB (0.60) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL25583964 | 0.83 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944929-B2 | UNA single stranded oligomers for therapeutics | ARCTURUS THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |