Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DUT | P33316 | 7/20 | 0.33 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.31 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.31 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.31 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA4 | P22748 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20407952 | 0.90 | POLB (0.55) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL20052004 | 0.90 | POLB (0.55) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL14143203 | 0.88 | POLB (0.47) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL13896528 | 0.81 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL20052005 | 0.78 | POLB (0.72) | POLBHSD17B10ALDH1A1LMNADUT | |
| SCHEMBL25712429 | 0.78 | P2RY2 (0.44) | — | |
| SCHEMBL25583964 | 0.77 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL23710654 | 0.76 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL19303349 | 0.76 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 | |
| SCHEMBL13471838 | 0.76 | POLB (0.52) | POLBHSD17B10PKMCRBNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3131914-B1 | 3'-SUBSTITUTED METHYL OR ALKYNYL NUCLEOSIDES FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS LLC (US) | 2023-05-10 | — | — | EP | disclosed |