Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.37 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | AHCY | P23526 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | VCP | P55072 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20407788 | 1.00 | KDM4E (0.47) | KDM4EMEN1KMT2ATSHRCDK5 | |
| SCHEMBL14867654 | 0.94 | KDM4E (0.44) | KDM4EMEN1KMT2ATSHRCDK5 | |
| SCHEMBL18525302 | 0.93 | KDM4E (0.45) | KDM4EMEN1KMT2ATSHRCDK5 | |
| SCHEMBL13443494 | 0.89 | KDM4E (0.45) | KDM4EMEN1KMT2ATSHRCDK5 | |
| SCHEMBL20052006 | 0.86 | KDM4E (0.40) | KDM4EMEN1KMT2ATSHRNOS1 | |
| SCHEMBL15763710 | 0.82 | CDK5 (0.48) | KDM4EMEN1KMT2ATSHRCDK5 | |
| SCHEMBL14867659 | 0.81 | KDM4E (0.39) | KDM4EMEN1KMT2ATSHRNOS1 | |
| SCHEMBL22083756 | 0.81 | KDM4E (0.47) | KDM4EMEN1KMT2ATSHRCDK5 | |
| SCHEMBL22571139 | 0.81 | KDM4E (0.47) | KDM4EMEN1KMT2ATSHRCDK5 | |
| SCHEMBL25652395 | 0.79 | KDM4E (0.43) | KDM4EMEN1KMT2ATSHRCDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944929-B2 | UNA single stranded oligomers for therapeutics | ARCTURUS THERAPEUTICS, INC. (US) | 2018-04-17 | — | — | US | disclosed |